Haotian Yan

Sep 30, 2024 | onlinelibrary.wiley.com | Li Bai |Haotian Yan |Yu Guo |Yong Shan

Introduction Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common hereditary cause of stroke.1 It results from mutations in the NOTCH3 gene located on chromosome 19q12.2 Magnetic resonance imaging (MRI) features of CADASIL include white matter hyperintensities (WMHs), lacune of presumed vascular origin (lacunes), and cerebral microbleeds (CMBs).3 Clinically, CADASIL is characterized by migraine, recurrent stroke, cognitive...