Haruhiko Koseki

Nov 19, 2023 | nature.com | XI LUO |Haruhiko Koseki |Enrico Glaab

AbstractThe vast majority of Parkinson’s disease cases are idiopathic. Unclear etiology and multifactorial nature complicate the comprehension of disease pathogenesis. Identification of early transcriptomic and metabolic alterations consistent across different idiopathic Parkinson’s disease (IPD) patients might reveal the potential basis of increased dopaminergic neuron vulnerability and primary disease mechanisms.