Harvard Combined

Jul 16, 2023 | jofskin.org | David A. Hashemi |Neal Bhatia |Harvard Combined

Main Article Content Keywords JAK inhibitor, janus kinase, atopic dermatitis, psoriasis, alopecia areata, vitiligo Abstract Janus kinases (JAKs) are non-receptor tyrosine kinases that work together with signal transducers and activators of transcription (STAT) proteins to form the JAK/STAT pathway. Together, this pathway is responsible for mediating a wide range of downstream cytokines and growth factors, and inhibition of various components of this pathway has been a major area of research...