Hayley Shaw

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The ERK5 MAP kinase regulates annexin complexes and membrane dynamics in embryonic stem cells

Jul 3, 2024 | biorxiv.org | Helen Brown |Charles Williams |Hayley Shaw |Ludivine Guillet

AbstractThe ERK5 MAP kinase signalling pathway controls key processes in mouse Embryonic Stem Cells (mESCs) maintenance, including expression of naive pluripotency genes and a transcriptional programme for stem cell rejuvenation. However, quantitative proteomics suggests that ERK5 signalling controls levels of proteins implicated in diverse biological processes.

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