Heather J Spence

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Metabolic adaptation following gastric bypass surgery: results from a 2-year observational study - International Journal of Obesity

Sep 2, 2024 | nature.com | Shu-Dong Zhang |Alexander D Miras |Heather J Spence

AbstractMetabolic adaptation is the lowering of basal metabolic rate (BMR) beyond what is predicted from changes in fat mass (FM) and fat-free mass (FFM) and may hamper weight-loss progression. It is unclear whether metabolic adaptation occurs following gastric bypass surgery (GBP) and if it persists. The aim of this study was to evaluate the reduction in BMR that is not explained by changes in body composition in patients following GBP compared to a weight-stable comparator group.

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