Hee Jin Jung

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Design and Synthesis of Novel 6-(Substituted phenyl)-[1,3]dioxolo[4′,5′:4,5]benzo[1,2-d]thiazole Compounds as Tyrosinase Inhibitors: In Vitro and In Vivo Insights

3 weeks ago | mdpi.com | Hyeon Seo Park |Hee Jin Jung |Hye Soo Park |Hye Jin Kim

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Design, Synthesis, and Anti-Tyrosinase, Anti-Melanogenic, and Antioxidant Activities of Novel (Z)-3-Benzyl-5-Benzylidene-2-Thioxothiazolidin-4-One Analogs

Jan 23, 2025 | mdpi.com | Hyeon Seo Park |Hee Jin Jung |Hye Soo Park |Hye Jin Kim

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Design, Synthesis, and Antioxidant and Anti-Tyrosinase Activities of (Z)-5-Benzylidene-2-(naphthalen-1-ylamino)thiazol-4(5H)-one Analogs: In Vitro and In Vivo Insights

Jan 13, 2025 | mdpi.com | Hee Jin Jung |Hye Jin Kim |Hyeon Seo Park |Hye Soo Park

1. IntroductionMelanin is a polymeric pigment that provides organisms with color and is abundant in various living organisms ranging from bacteria to humans [1]. In humans, excluding neuromelanin, melanin is divided into two types: eumelanin, which has a 5,6-dihydroxyindole structure (black to brown), and pheomelanin, which has a benzothiazine or benzothiazole structure (red to yellow) [2,3,4]. These two melanins greatly influence the determination of skin color.
Design, Synthesis, and Anti-Melanogenic Activity of 2-Mercaptomethylbenzo[d]imidazole Derivatives Serving as Tyrosinase Inhibitors: An In Silico, In Vitro, and In Vivo Exploration

Oct 16, 2024 | mdpi.com | Hee Jin Jung |Hyeon Seo Park |Hye Jin Kim |Hye Soo Park

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
8-Prenylgenistein Isoflavone in Cheonggukjang Acts as a Novel AMPK Activator Attenuating Hepatic Steatosis by Enhancing the SIRT1-Mediated Pathway

Sep 8, 2024 | mdpi.com | Hee Jin Jung |Sang Noh |Hyun Kim |Radha Arulkumar

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Molecules | Free Full-Text | Exploration of Compounds with 2-Phenylbenzo[d]oxazole Scaffold as Potential Skin-Lightening Agents through Inhibition of Melanin Biosynthesis and Tyrosinase Activity

Sep 2, 2024 | mdpi.com | Hee Jin Jung |Hye Soo Park |Hye Jin Kim |Hyeon Seo Park

1. IntroductionMelanin is a pigment that varies in color from a red-yellow to black-brown pigment and is found in nearly all living organisms, including bacteria, plants, animals, and humans [1,2]. Melanin is an oligomer or polymer. Eumelanin has a 5,6-dihydroxyindole structure, whereas pheomelanin contains benzothiazine and benzothiazole structures [3]. Melanin determines the color of the skin, eyes, and hair [4] and plays a protective role by absorbing ultraviolet rays [5].
Antioxidants | Free Full-Text | Anti-Browning Effect of 2-Mercaptobenzo[d]imidazole Analogs with Antioxidant Activity on Freshly-Cut Apple Slices and Their Highly Potent Tyrosinase Inhibitory Activity

Sep 29, 2023 | mdpi.com | Jieun Lee |Hye Soo Park |Hee Jin Jung |Yu Jung Park

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Hee Jin Jung

Articles

Design and Synthesis of Novel 6-(Substituted phenyl)-[1,3]dioxolo[4′,5′:4,5]benzo[1,2-d]thiazole Compounds as Tyrosinase Inhibitors: In Vitro and In Vivo Insights

Design, Synthesis, and Anti-Tyrosinase, Anti-Melanogenic, and Antioxidant Activities of Novel (Z)-3-Benzyl-5-Benzylidene-2-Thioxothiazolidin-4-One Analogs

Design, Synthesis, and Antioxidant and Anti-Tyrosinase Activities of (Z)-5-Benzylidene-2-(naphthalen-1-ylamino)thiazol-4(5H)-one Analogs: In Vitro and In Vivo Insights

Design, Synthesis, and Anti-Melanogenic Activity of 2-Mercaptomethylbenzo[d]imidazole Derivatives Serving as Tyrosinase Inhibitors: An In Silico, In Vitro, and In Vivo Exploration

8-Prenylgenistein Isoflavone in Cheonggukjang Acts as a Novel AMPK Activator Attenuating Hepatic Steatosis by Enhancing the SIRT1-Mediated Pathway

Molecules | Free Full-Text | Exploration of Compounds with 2-Phenylbenzo[d]oxazole Scaffold as Potential Skin-Lightening Agents through Inhibition of Melanin Biosynthesis and Tyrosinase Activity

Antioxidants | Free Full-Text | Anti-Browning Effect of 2-Mercaptobenzo[d]imidazole Analogs with Antioxidant Activity on Freshly-Cut Apple Slices and Their Highly Potent Tyrosinase Inhibitory Activity

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