Helena Chaytow

1 week ago | science.org | Fabio Lauria |Helena Chaytow |Yu-Ting Huang |Rachel Kline

Editor’s summaryThe development of neuromuscular junctions (NMJs) involves the selective pruning of muscle fiber–innervating axons such that only one axon innervates each muscle fiber. Van der Hoorn et al. monitored translation, the process of active protein synthesis from mRNAs, in motor neurons in early postnatal mice and characterized the “translatome” that emerges and changes during synaptic pruning.