Hiroaki Tanaka

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Articles

Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping

Jan 11, 2024 | ard.bmj.com | Hiroaki Tanaka |Yukinori Okada |Shingo Nakayamada |Yusuke Miyazaki

IntroductionAutoimmune rheumatic diseases (AIRDs) are systemic diseases characterised by orchestration of disrupted self-tolerance of immune systems, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).1 2 Given shared immunological backgrounds across AIRDs, glucocorticoid and immunosuppressive drugs have been conventionally used for treatment.
Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping

Oct 30, 2023 | ard.bmj.com | Hiroaki Tanaka |Yukinori Okada |Shingo Nakayamada |Yusuke Miyazaki

DiscussionsIn this study, we evaluated the large-scale and cohort-based immunophenotype dataset over 1000 individuals and 11 AIRDs with deep and longitudinal clinical information.

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