Hoda Pourhassan

2 weeks ago | onlinelibrary.wiley.com | Vaibhav Agrawal |Shukaib Arslan |Hoda Pourhassan |Paul Koller

CONFLICT OF INTEREST STATEMENT The authors have no conflicts of interest to declare. REFERENCES 1, , , , . Acute leukemia incidence and patient survival among children and adults in the United States, 2001–2007. Blood. 2012; 119(1): 34–43. 2, . Management of adults with T-cell lymphoblastic leukemia. Blood. 2017; 129(9): 1134–1142. 3, , , , , , et al. Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. Lancet Oncol. 2009; 10(2): 147–156.

May 29, 2024 | onlinelibrary.wiley.com | Tamer Othman |Paul Koller |Hoda Pourhassan |Vaibhav Agrawal

Corresponding Author Ibrahim Aldoss Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California, USA Correspondence Ibrahim Aldoss, Division of Leukemia, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA 91010, USA. Email: [email protected] for more papers by this author

Sep 29, 2023 | onlinelibrary.wiley.com | Vaibhav Agrawal |Lindsey Murphy |Hoda Pourhassan |Vinod Pullarkat

What is the new aspect of your work? This is a comprehensive review of practical approaches to optimize outcomes with CD19-directed CAR-T cell therapy in adults with relapsed/refractory B-cell ALL. What is the central finding of your work? CAR-T cell therapy has demonstrated high response rates in adult R/R B-ALL and studies have identified factors predictive of response and toxicity, but relapse after CAR-T therapy remains a substantial concern.