Hong-Yun Shang

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SOI: Robust identification of orthologous synteny with the Orthology Index and broad applications in evolutionary genomics

Dec 7, 2024 | biorxiv.org | Ren-Gang Zhang |Hong-Yun Shang |Richard Milne |Fabricio Almeida-Silva

AbstractWith the explosive growth of whole-genome datasets, the accurate detection of orthologous synteny has become crucial for the reconstruction of evolutionary history. However, the currently available methods for the identification of orthologous synteny have great limitations: the methods are difficult to scale with varying polyploidy histories, and the accurate removal of out-paralogy is challenging.

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