Hongsheng Wang

Nov 21, 2024 | nature.com | Hui Chen |Stéphanie Moriceau |Peng Liu |Thierry Brue |Hongsheng Wang |Yuting Ma | +3 more

AbstractCushing’s syndrome is caused by an elevation of endogenous or pharmacologically administered glucocorticoids. Acyl coenzyme A binding protein (ACBP, encoded by the gene diazepam binding inhibitor, Dbi) stimulates food intake and lipo-anabolic reactions. Here we found that plasma ACBP/DBI concentrations were elevated in patients and mice with Cushing’s syndrome.

Mar 5, 2024 | nature.com | Hongsheng Wang

AbstractN6-methyladenosine (m6A) and its associated reader protein insulin like growth factor 2 mRNA binding protein 3 (IGF2BP3) are involved in tumor initiation and progression via regulating RNA metabolism. This study aims to investigate the biological function and clinical significance of IGF2BP3 in gastric cancer (GC). The clinical significance of IGF2BP3 was evaluated using tumor related databases and clinical tissues.

May 3, 2023 | frontiersin.org | Related Diseases |Shanghai Jiaotong |Jorge Cervantes |Hongsheng Wang

1. Introduction Tuberculosis (TB) is a chronic disease that is caused by a Mycobacterium tuberculosis (MTB) infection and has become a serious and urgent public health problem in the world. The vast majority of infected people are said to be in a state of latent tuberculosis infection (LTBI) without exhibiting any signs or symptoms, 5–10% of whom will develop active tuberculosis (ATB) throughout their lives if they are out of the preventive intervention (1).