Huiqian Yu

Nov 28, 2023 | onlinelibrary.wiley.com | Chenhong Xue |Jinfa Dou |Shuzhen Zhang |Huiqian Yu

Shikonin, a major component of Lithospermum erythrorhizon, exerts anti-inflammatory and antibacterial effects and expedites wound healing. This study aims to evaluate the anti-inflammatory and antioxidant activities of shikonin in a Sprague–Dawley rat model and cell models using fibroblast and endothelial cells. The impact of shikonin on the activity of endothelial cells and fibroblasts was examined by cell counting kit 8 and wound-healing assays.