Huiyun Lyu

Dec 6, 2023 | elifesciences.org | Guohua Yuan |Xinyi Liu |Xiaobo Wang |Huiyun Lyu

eLife assessment This study presents the valuable finding that sustained calcium signaling in induced-Treg (iTreg) cells can lead to the loss of Foxp3 expression and iTreg identity by altering the chromatin landscape. The evidence supporting the claims of the authors is convincing. The work will be of interest to immunologists working on Treg cell therapy.