
Hung N. Do
Articles
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Jul 23, 2024 |
dx.doi.org | Jinan Wang |Hung N. Do |Yinglong Miao |Kushal Koirala
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Jul 23, 2024 |
pubs.acs.org | Jinan Wang |Kushal Koirala |Hung N. Do |Yinglong Miao
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Feb 14, 2023 |
nature.com | Michael Wolfe |Hung N. Do
AbstractPresenilin-1 (PS1) is the catalytic subunit of γ-secretase which cleaves within the transmembrane domain of over 150 peptide substrates. Dominant missense mutations in PS1 cause early-onset familial Alzheimer’s disease (FAD); however, the exact pathogenic mechanism remains unknown.
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