Hwaseok Hong

Jan 2, 2025 | science.org | Hogyun Seo |Hwaseok Hong |Jiyoung Park |Seul Lee |Dongwoo Ki |Hye-Young Sagong | +2 more

Published In ScienceVolume 387 | Issue 67293 January 2025Article versionsSubmission historyReceived: 4 April 2024Accepted: 8 November 2024Published in print: 3 January 2025PermissionsRequest permissions for this article. AcknowledgmentsWe thank the staff of beamline 7A at the Pohang Accelerator Laboratory, Pohang (South Korea), for their assistance during data collection and are grateful to all researchers for continuous discussions on the manuscript. We would also like to thank M. Cummins and G.

Apr 1, 2024 | biorxiv.org | Hogyun Seo |Hwaseok Hong |Jiyoung Park |Seul Lee

AbstractSince the demonstration that rapid polyethylene terephthalate (PET) decomposition using enzymes is feasible, a number of efficient depolymerases have been reported with the aim of resolving the plastic pollution issues. However, sporadic studies on enzymes with PET hydrolysis activity hinder the understanding of the distribution of potential PETases hidden in nature's repertoire, and subsequently, the identification of potent enzymes.

Jul 28, 2023 | nature.com | Hogyun Seo |Jiyoung Park |Jaewon Jang |Hwaseok Hong |Dongwoo Ki

AbstractExcessive polyethylene terephthalate (PET) waste causes a variety of problems. Extensive research focused on the development of superior PET hydrolases for PET biorecycling has been conducted. However, template enzymes employed in enzyme engineering mainly focused on IsPETase and leaf-branch compost cutinase, which exhibit mesophilic and thermophilic hydrolytic properties, respectively.