Ian Glaspole

Oct 10, 2024 | thorax.bmj.com | Andrew Li |Alan Teoh |Lauren Troy |Ian Glaspole

DiscussionWhen compared with the ECSC/Miller reference equations, applying the GLI reference equations among patients with ILD consistently demonstrated higher DLCO percentage predicted values (mean 4.9% higher) and smaller lung volume percentage predicted values (mean 8.8% lower FVC) overall and when stratified by diagnosis, sex and ethnicity. This led to disagreement rates in severity classification of 9.3%, 10.0% and 7.3% for FVC, FEV1 and DLCO, respectively.

Sep 24, 2024 | thorax.bmj.com | Andrew Li |Alan Teoh |Lauren Troy |Ian Glaspole

AbstractBackground Lung function testing remains a cornerstone in the assessment and management of interstitial lung disease (ILD) patients. The clinical implications of the Global Lung function Initiative (GLI) reference equations and the updated interpretation strategies remain uncertain. Methods Adult patients with ILD with baseline forced vital capacity (FVC) were included from the Australasian ILD registry and the National Healthcare Group ILD registry, Singapore.