Inderpaul Singh Sehgal

Sep 25, 2024 | err.ersjournals.com | Inderpaul Singh Sehgal

DiscussionWe found that SNPs in over 50 genes or regions have been linked to IPF in genomic DNA studies. Most genetic variants were in the noncoding regions of the genome. The mechanisms by which the implicated genes contribute to pulmonary fibrosis have been elucidated in less than half of them. Most variants reported here have been discovered in GWASs using a “hypothesis-free” approach. Only 22 of the 88 SNPs had odds ratios of >1.5 or <0.67 suggesting moderate–large effect sizes (table 2).

Mar 7, 2024 | erj.ersjournals.com | Inderpaul Singh Sehgal |David W. Denning |Sanjay H. Chotirmall |James Chalmers

FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.

Feb 29, 2024 | erj.ersjournals.com | Inderpaul Singh Sehgal |David W. Denning |Sanjay H. Chotirmall |James Chalmers

AbstractBackground The ISHAM working group proposed recommendations for managing allergic bronchopulmonary aspergillosis (ABPA) nearly a decade ago. There is a need to update these recommendations due to advances in diagnostics and therapeutics.

Jan 18, 2024 | erj.ersjournals.com | Inderpaul Singh Sehgal

FootnotesConflict of interest: The authors have no potential conflicts of interest to disclose. Received December 9, 2023. Accepted December 11, 2023. View Full Text ERS Members myERS - ERS members : log in with your myERS username and password. INDIVIDUALS  Login as an individual user. Forgot your username or password?

Sep 10, 2023 | erj.ersjournals.com | Inderpaul Singh Sehgal

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