Irene Zebochin

Aug 12, 2024 | biorxiv.org | Yuening Li |Amy Lock |Laura Fedele |Irene Zebochin

AbstractPeripheral sensitization of nociceptors is believed to be a key driver of chronic pain states. Here, we sought to study the effects of a modified version of inflammatory soup on the excitability of human stem-cell derived sensory neurons. For this, we used a pre-existing and a novel stem cell line, modified to stably express the calcium sensor GCamP6f.