Isabel M. Martins

Jan 5, 2025 | mdpi.com | Isabel M. Martins

1. IntroductionThe concept of diffuse noxious inhibitory control (DNIC) first appeared in the field of pain research through the studies of Le Bars et al. [1,2,3,4,5]. DNIC is known as a paradigm of endogenous analgesia that is driven by the “pain inhibits pain” principle. This experience occurs when an additional painful stimulus in one part of the body suppresses the initial spatially distant experienced pain [6,7].

Mar 17, 2023 | mdpi.com | Julia Kessler |Alírio E. Rodrigues |Yaidelin A. Manrique |Isabel M. Martins

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle byJúlia C. Kessler 1,2,3,4, Yaidelin A. Manrique 1,2, Isabel M. Martins 1,2,*, Alírio E. Rodrigues 1,2, Maria Filomena Barreiro 3,4 and Madalena M.