Isabel Risch

Jan 23, 2025 | cell.com | Hao Chen |Cole J. Ferguson |Dylan Mitchell |Isabel Risch |Amanda Titus |João Paulo | +12 more

Keywords ubiquitin deubiquitinase USP7 Hao-Fountain syndrome HAFOUS p53 brain development synapse TMT proteomics Ppil4 RNA splicing Research topic(s) CP: Neuroscience CP: Molecular biology Introduction As a fundamental post-translational modification, protein ubiquitination plays critical roles in neuronal development and function, and deregulation of ubiquitination is thought to contribute to the pathogenesis of diverse neurological conditions, including Angelman,1 Gordon-Holmes,2,3 and...