Isabella Ciccone

New York

Assistant Editor at MJH Life Sciences

Assistant Editor, @neurology_live 🧠 | @TCNJ Alum 🦁 | Former @rutgersifh Research Assistant 🔬 | 📧 [email protected] | Views are my own.

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Articles

Observed Differences in PIRA Definition Call for More Standardized Agreement on Term

1 day ago | neurologylive.com | Isabella Ciccone

Newly published in JAMA Neurology, a retrospective cohort study using MSBase registry data that compared 360 definitions of progression independent of relapse activity (PIRA) in patients with relapsing-remitting multiple sclerosis (MS) reported substantial differences in PIRA incidence and persistence depending on definition parameters.The study suggests that a proposed standardized definition could improve consistency and comparability across future MS research.1 Overall, the analysis...
A Mother’s Journey Through Diagnosis and Acceptance of Duchenne Muscular Dystrophy: Debra Miller

2 days ago | neurologylive.com | Debra Miller |Isabella Ciccone

CommentaryVideoMay 13, 2025Author(s):,Fact checked by:The chief executive officer and founder at CureDuchenne shared her emotional journey from her son’s diagnosis of Duchenne to embracing a new path focused on advocacy, adaptation, and resilience. [WATCH TIME: 4 minutes]WATCH TIME: 4 minutes"As a mom, you lead with love and where that takes you is completely off the path that you thought you had.
The Role of Aging in Multiple Sclerosis Care

3 days ago | neurologylive.com | Marisa McGinley |Devon Conway |Moein Amin |Isabella Ciccone

WATCH TIME: 5 minutesThe 2025 Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum, held February 27 to March 1, in West Palm Beach, Florida. This CE-accredited meeting featured a single track of scientific and clinical presentations focused on advancing research and treatment for multiple sclerosis (MS) and related disorders.
Interim Analysis Reveals Long-Term Efficacy and Safety of Pitolisant in Narcolepsy Types 1 and 2

3 days ago | neurologylive.com | Isabella Ciccone

Newly published Sleep Medicine, an interim analysis from a long-term, post authorization safety study European study reported that pitolisant (Wakix; Harmony Biosciences), an approved treatment for excessive daytime sleepiness (EDS) in pediatric patients with narcolepsy, demonstrated safety, tolerability and efficacy among patients with narcolepsy type 1 (NT1) and type 2 (NT2) after 42.6 months of follow-up.1 In this analysis, investigators included 370 patients with narcolepsy (mean age, 40...
AI and Machine Learning in MS: Promise and Practicality for Clinical Practice

3 days ago | neurologylive.com | Marisa McGinley |Devon Conway |Moein Amin |Isabella Ciccone

WATCH TIME: 9 minutesThe 2025 Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum, held February 27 to March 1, in West Palm Beach, Florida. This CE-accredited meeting featured a single track of scientific and clinical presentations focused on advancing research and treatment for multiple sclerosis (MS) and related disorders.
Serum Neurofilament Light Chain Limited in Predicting MOGAD Attacks but Correlates With Attack Severity

3 days ago | neurologylive.com | Isabella Ciccone

A recently published systematic review reported that serum neurofilament light chain (sNfL) levels were elevated in patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), particularly during clinical attacks and in those with brain lesions, but had limited ability to predict relapse or differentiate MOGAD from related demyelinating diseases.1 Published in Multiple Sclerosis and Related Disorders, the review analyzed 23 original research articles comprising data...
Emerging Therapies and the Future of MS: Insights on BTK Inhibitors and CAR T-Cells

4 days ago | neurologylive.com | Marisa McGinley |Devon Conway |Moein Amin |Isabella Ciccone

WATCH TIME: 8 minutesThe 2025 Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum, held February 27 to March 1, in West Palm Beach, Florida. This CE-accredited meeting featured a single track of scientific and clinical presentations focused on advancing research and treatment for multiple sclerosis (MS) and related disorders.
Expanding Access to Whole Genome Sequencing in Parkinson Research

4 days ago | cgtlive.com | James Beck |Noah Stansfield |Isabella Ciccone

The PD GENEration study, which is led by the Parkinson’s Foundation in collaboration with the Global Parkinson’s Genetics Program (GP2), provides whole genome sequencing (WGS) and genetic counseling for patients with Parkinson disease (PD) across more than 8 countries in the Americas and Israel. In order to support expansion internationally, the study adapted counseling materials tailored to local languages, cultural contexts, and healthcare infrastructure.
South Korea Nationwide Study Reveals Elevated Risk of Autoimmune Rheumatic Diseases in MS and NMOSD

4 days ago | neurologylive.com | Isabella Ciccone

A newly published analysis of national health data between 2010 and 2017 from the Korean National Health Insurance Service revealed that patients with multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) had an increased risk of developing autoimmune rheumatic diseases (ARDs) compared with matched controls.1 Using diagnostic codes and registry information, researchers identified patients with MS and NMOSD and compared them with matched control groups at a 1:10 ratio...
Evolving Approaches to the Diagnosis and Management of Paraneoplastic Neurologic Syndromes: Ditte Primdahl, MD; Shailee Samir Shah, MD

6 days ago | neurologylive.com | Ditte Primdahl |Shailee Shah |Isabella Ciccone |Luke Halpern

WATCH TIME: 4 minutes“We want to treat their underlying cancer, but we also want to treat their paraneoplastic syndrome. So, figuring out that perfect balance there is going to be key.”Managing paraneoplastic neurologic syndromes (PNS) in the era of cancer immunotherapy can present unique challenges because of the interplay between oncologic treatments and immune-mediated neurological complications.

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Isabella Ciccone, MPH @iciccone7

17 Apr 25

RT @neurology_live: Take a look at NeurologyLive's latest feature📖: a sneak peek into Cleveland Clinic's upcoming Neurological Institute, a…

Isabella Ciccone, MPH @iciccone7

10 Apr 25

RT @neurology_live: 🙌🧠Thank you @AgneStraukiene for taking over the NeurologyLive X Channel during the 2025 #AANAM in San Diego, California…

Isabella Ciccone, MPH @iciccone7

8 Apr 25

RT @neurology_live: That’s wrap by Dr @AgneStraukiene from #AAN2025 in sunny San Diego! ☀️ From HSCT to Frexalimab, aging & DMTs—MS scienc…

Isabella Ciccone

Articles

Observed Differences in PIRA Definition Call for More Standardized Agreement on Term

A Mother’s Journey Through Diagnosis and Acceptance of Duchenne Muscular Dystrophy: Debra Miller

The Role of Aging in Multiple Sclerosis Care

Interim Analysis Reveals Long-Term Efficacy and Safety of Pitolisant in Narcolepsy Types 1 and 2

AI and Machine Learning in MS: Promise and Practicality for Clinical Practice

Serum Neurofilament Light Chain Limited in Predicting MOGAD Attacks but Correlates With Attack Severity

Emerging Therapies and the Future of MS: Insights on BTK Inhibitors and CAR T-Cells

Expanding Access to Whole Genome Sequencing in Parkinson Research

South Korea Nationwide Study Reveals Elevated Risk of Autoimmune Rheumatic Diseases in MS and NMOSD

Evolving Approaches to the Diagnosis and Management of Paraneoplastic Neurologic Syndromes: Ditte Primdahl, MD; Shailee Samir Shah, MD

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