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  • Nov 8, 2023 | frontiersin.org | Isabelle Meyts

    Human Inborn Errors of Immunity (IEI) represent a diverse array of genetic disorders affecting the immune system and result in increased susceptibility to infections, autoinflammation, autoimmunity, allergies, and/or malignancies (1, 2). To date, a total of 485 genetic defects that cause IEI have been identified (3), with over two-thirds of them being associated with dysregulated antibody production (4).

  • Aug 9, 2023 | nejm.org | Stuart G. Tangye |Isabelle Meyts |Elizabeth G. Phimister

    From the Garvan Institute of Medical Research, Darlinghurst, NSW, and the School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales Sydney, Randwick, NSW — both in Australia (S.G.T.); and the Department of Immunology and Microbiology, Laboratory for Inborn Errors of Immunity, and the Department of Pediatrics, University Hospitals, Leuven, and Fonds voor Wetenschappelijk Onderzoek Vlaanderen, Brussels — all in Belgium (I.M.).

  • May 11, 2023 | frontiersin.org | Giles Laboratory |Paris Sorbonne Cité |Isabelle Meyts

    Malgorzata Pac1*, Jean-Laurent Casanova2,3,4,5, Irina Tuzankina6 and László Maródi2,7 1Department of Immunology, The Children’s Memorial Health Institute, Warsaw, Poland 2St. Giles Laboratory of Human Genetics of Infectious Diseases, The Rockefeller University, New York, NY, United States 3Howard Hughes Medical Institute, New York, NY, United States 4Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Necker Hospital for Sick Children and Institut National de la Sante et de la...

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