Ishaque Pulikkal Kadamberi

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Eukaryotic Translation Initiation Factor Loaded Extracellular Vesicles Promotes Macrophage Cholesterol Metabolism in ovarian cancer

Dec 11, 2024 | biorxiv.org | Sonam Mittal |Minal Nenwani |Sudhir Kumar |Ishaque Pulikkal Kadamberi

AbstractTumor-driven immune suppression poses a significant impediment to the success of immunotherapy in ovarian cancer. Among the various mechanisms contributing to immune suppression, intracellular communication facilitated by tumor-derived extracellular vesicles (EVs) within the tumor microenvironment (TME) emerges as a pivotal factor influencing tumor growth.

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