Jack C. Sharland

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Diversity Synthesis Using Glutarimides as Rhodium Carbene Precursors in Enantioselective C–H Functionalization and Cyclopropanation

1 month ago | dx.doi.org | William Tracy |Jack C. Sharland |Duc Viet Ly |Djamaladdin G. Musaev

IntroductionClick to copy section linkSection link copied!Cereblon E3 ligase modulatory drugs (CELMoDs) are an important class of compounds capable of the highly effective targeted degradation of proteins of interest. (1) Interest in the development of novel CELMoDs has expanded rapidly in recent years due to their utility in the treatment of cancer and other diseases.
Diversity Synthesis Using Glutarimides as Rhodium Carbene Precursors in Enantioselective C–H Functionalization and Cyclopropanation

1 month ago | pubs.acs.org | William Tracy |Jack C. Sharland |Duc Viet Ly |Djamaladdin G. Musaev

IntroductionClick to copy section linkSection link copied!Cereblon E3 ligase modulatory drugs (CELMoDs) are an important class of compounds capable of the highly effective targeted degradation of proteins of interest. (1) Interest in the development of novel CELMoDs has expanded rapidly in recent years due to their utility in the treatment of cancer and other diseases.

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