Jake shortt

May 30, 2024 | onlinelibrary.wiley.com | Jake shortt |Stephen Opat

In their paper the authors report their experience applying the EuroClonality NGS DNA Capture (EuroClonality-NDC) assay to plasma from diffuse large B-cell lymphoma (DLBCL) patients receiving first-line chemoimmunotherapy.1 This study further adds to the evidence for the use of liquid biopsy in lymphoma management, as previously demonstrated with other NGS-based platforms.2-4 Of note, this is the first publication utilising cell-free tumour DNA (ctDNA) as input to the EuroClonality-NDC assay,...

Aug 30, 2023 | nejm.org | Jake shortt |Elizabeth G. Phimister

August 30, 2023 DOI: 10.1056/NEJMe2307370Elizabeth G. Phimister, Ph.D., Editor This editorial describes the science behind a study of mezigdomide, which augments the degradation of the proteins Ikaros and Aiolos, to treat multiple myeloma. Funding and Disclosures Disclosure forms provided by the author are available with the full text of this editorial at NEJM.org. This editorial was published on August 30, 2023, at NEJM.org.