James A Berkley

May 9, 2024 | nature.com | Basil Britto Xavier |Emmanuel Roilides |Maia De Luca |James A Berkley |Charalampos Zarras |Andrew Whitelaw | +7 more

AbstractGram-negative bacteria (GNB) are a major cause of neonatal sepsis in low- and middle-income countries (LMICs). Although the World Health Organization (WHO) reports that over 80% of these sepsis deaths could be prevented through improved treatment, the efficacy of the currently recommended first- and second-line treatment regimens for this condition is increasingly affected by high rates of drug resistance.