Japan JAPAN

3 weeks ago | onlinelibrary.wiley.com | Koshiro Sonomoto |Japan JAPAN |Yoshiya Tanaka

1 Introduction As Japan leads the world in population aging, the healthcare landscape is facing unprecedented challenges, particularly in the management of chronic diseases such as rheumatoid arthritis (RA). In Japan, demographic change has led to a marked increase in the proportion of RA patients aged 65 years and older, many of whom are further burdened by comorbidities such as chronic kidney disease, cardiovascular disease, lung disease, and a history of serious infections [1].