Jarish N. Cohen

2 months ago | onlinelibrary.wiley.com | Phoebe E Leboit |Dhara Patel |Jarish N. Cohen |Madison I Moss

1 Introduction Hidradenitis suppurativa (HS) is an inflammatory skin disease that affects approximately 1% of the global population and disproportionately impacts women and marginalised groups [1, 2]. HS is caused by a combination of genetic, immune, endocrine, and environmental factors, with specific risk factors including obesity, smoking, and a family history of the disease [3, 4].

Jul 23, 2024 | biorxiv.org | Dhara Patel |Jarish N. Cohen |Madison I Moss |Phoebe E Leboit

AbstractHidradenitis Suppurativa (HS) is a relatively common and highly morbid inflammatory skin disease. Due to our relatively limited understanding of HS's pathogenesis, there are currently insufficient treatment options available, and many patients' medical needs are not being met. This is partly due to a scarcity of ex vivo human assays and animal models that accurately recapitulate the disease.