Javier Martinez‐Lopez

Oct 29, 2024 | acrjournals.onlinelibrary.wiley.com | Javier Martinez‐Lopez |Martin Kerick |Guillermo Barturen |Lorenzo Beretta |Isabel Almeida |Lourdes Ortiz‐Fernandez | +4 more

INTRODUCTION Systemic sclerosis (SSc) is a rare immune-mediated inflammatory disease (IMID) characterized by immune dysregulation, vasculopathy, and cutaneous and internal fibrosis.1 SSc is an heterogeneous disorder affecting the connective tissue from which patients can be classified based on the extension of fibrosis as having limited cutaneous SSc (lcSSc) or diffuse cutaneous SSc or by their serological status.2 Recent genome-wide association studies (GWASs) have identified multiple...