Jeffrey A. Zuccato

Oct 8, 2024 | nature.com | Jeffrey A. Zuccato |Yasin Mamatjan |Ammara Muazzam |Craig Simpson |Ming S. Tsao |Kenneth Aldape | +3 more

AbstractBrain metastases (BMs) are the most common and among the deadliest brain tumors. Currently, there are no reliable predictors of BM development from primary cancer, which limits early intervention. Lung adenocarcinoma (LUAD) is the most common BM source and here we obtained 402 tumor and plasma samples from a large cohort of patients with LUAD with or without BM (n = 346).