Jennifer Tsang

2 weeks ago | drugdiscoverynews.com | Jennifer Tsang

By using phages to deliver genes for therapeutic proteins, biologic drug delivery could become much easier. Credit: iStock.com/Marharyta MarkoBy using phages to deliver genes for therapeutic proteins, biologic drug delivery could become much easier. | 4 min readJennifer Tsang, PhDRegister for free to listen to this articleBiologic drugs have opened the door to treating diseases that were once considered difficult or impossible to treat.

1 month ago | drugdiscoverynews.com | Jennifer Tsang

Postpartum depression (PPD) affects nearly 20 percent of childbearing people, but just three percent receive treatment until their symptoms resolve (1,2). Lauren Osborne, a reproductive psychiatrist at Weill Cornell Medicine/New York-Presbyterian Hospital said that this is partly because “we aren't good at figuring out who's going to be at risk and getting them into care early.” What if there was a way to better predict and treat people before PPD develops?

2 months ago | drugdiscoverynews.com | Jennifer Tsang

New phenotypic methods can help identify the best antibiotic to treat sepsis, UTIs, and other bacterial infections. Credit: Martin Oeggerli (Micronaut) and Resistell 2021New phenotypic methods can help identify the best antibiotic to treat sepsis, UTIs, and other bacterial infections.

2 months ago | drugdiscoverynews.com | Jennifer Tsang

In vivo studies of the antibiotic darobactin D22 against high-priority gram-negative bacteria show promise for further drug development. In vivo studies of the antibiotic darobactin D22 against high-priority gram-negative bacteria show promise for further drug development. | 3 min readJennifer Tsang, PhDRegister for free to listen to this articleIn the innermost layer of a parasitic worm sits the starting material for what may become a powerful new antibiotic.

2 months ago | synbiobeta.com | Jennifer Tsang

Since the discovery of Cas9, scientists have been identifying other CRISPR enzymes in attempts to find enzymes that are better fit for purpose - those that cut more efficiently, those that are smaller and thus easier to package in gene therapy vectors, or those that have minimal off-target editing. Scientists have been optimizing CRISPR systems for years, and now, with the rise of AI in biotech, many in the field have been using AI to design the best CRISPR system.