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1 week ago | 
medicalxpress.com | Jenny Blair
For women aged 40 to 74, a mammogram every year or every other year is the standard recommendation in screening for breast cancer. Regular mammograms reduce the risk of late-stage breast cancer and improve breast cancer survival rates. But the guidance has been less clear for women aged 75 and older.
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1 week ago | 
ysph.yale.edu | Jenny Blair
An emerging oncology tool known as broad genomic profiling or BGP is increasingly being used to help identify targeted therapies for patients diagnosed with cancer. Rather than analyzing one gene at a time for mutations that could be related to a patient’s cancer, BGP examines multiple genes in a tumor sample all at once. This comprehensive analysis helps health care providers better understand a tumor’s entire genetic makeup so they can prescribe targeted therapies to attack the disease.
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Jan 15, 2025 | 
medscape.co.uk | Jenny Blair
This site is intended for UK healthcare professionals MEDBRIEFTOPLINE:Children with a history of self-harm who present for services need assessments for life stressors and deprivation, mental illness, and substance misuse. Appropriate referrals should be made. Guidelines for self-harm management are laid out by the National Institute for Health and Care Excellence.
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Jan 14, 2025 | 
medscape.co.uk | Jenny Blair
This site is intended for UK healthcare professionals MEDBRIEFTOPLINE:The evidence base around drug interventions to bring down high blood potassium levels is modest, but is most supportive of insulin plus glucose, inhaled or intravenous salbutamol, or a combination. METHODOLOGY:A systematic review and meta-analysis of 101 studies that assessed drug treatments for acute hyperkalaemia (1977-2024).
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Jan 13, 2025 | 
medscape.co.uk | Jenny Blair
This site is intended for UK healthcare professionals MEDBRIEFTOPLINE:Among women of childbearing age, low iodine intake is associated with a higher risk of developing hypertension during at least the decade after giving birth. METHODOLOGY:A sub-study within the prospective, population-based, Norwegian Mother, Father, and Child Cohort Study. The authors followed 58,629 women without baseline thyroid dysfunction or hypertension after delivery.
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Jan 10, 2025 | 
medscape.co.uk | Jenny Blair
This site is intended for UK healthcare professionals MEDBRIEFTOPLINE:Artificial intelligence (AI)-enhanced ECG can estimate risk for hypertension as well risk stratification once hypertension is diagnosed. Such a tool might help clinicians to more closely monitor higher-risk patients. METHODOLOGY:Development and external validation prognostic cohort study of a new AI ECG tool called AIRE-HTN.
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Jan 9, 2025 | 
medscape.co.uk | Jenny Blair
This site is intended for UK healthcare professionals MEDBRIEFTOPLINE:Although bereavement in childhood is a severe stressor, it appears to have no association with childhood new-onset type 1 diabetes in Sweden. METHODOLOGY:A prospective cohort study of registry data on children born in Sweden during 1987-2020 (n = 3,598,159). The authors followed children who lost a parent or sibling from age 1 to 18 years.
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Jan 8, 2025 | 
medscape.co.uk | Jenny Blair
This site is intended for UK healthcare professionals MEDBRIEFTOPLINE:For children born in the United Kingdom after 28 weeks of gestation, care in a birth unit colocated with a local neonatal unit (LNU), especially a high-volume unit, may be as safe as in a unit colocated with a neonatal intensive care unit (NICU). Earlier births are safer near a NICU. METHODOLOGY:The retrospective OPTI-PREM study of both types of care settings in the United Kingdom.
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Jan 7, 2025 | 
medscape.co.uk | Jenny Blair
This site is intended for UK healthcare professionals MEDBRIEFTOPLINE:For patients experiencing major trauma in England and requiring a secure airway, time to rapid sequence intubation (RSI) and tracheal intubation occurred earlier via pre-hospital helicopter services than in the emergency department. METHODOLOGY:A retrospective cohort study of 209 trauma patients who underwent RSI and tracheal intubation over a 2-year period in a mixed rural and urban region.
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Dec 11, 2024 | 
medscape.co.uk | Jenny Blair
This site is intended for UK healthcare professionals MEDBRIEFTOPLINE:School-age children born preterm with grade 2-3 bronchopulmonary dysplasia (BPD) have a worse quality of life (QOL), especially those experiencing asthma symptoms. Targeted interventions might help. METHODOLOGY:A prospective observational study of 102 children born before 32 weeks' gestation and admitted to neonatal intensive care (2012-2014). Population included children with and without BPD.
