Jeremy Axelrod

Aug 6, 2024 | biorxiv.org | Jonathan Remis |Petar Petrov |Jessie Zhang |Jeremy Axelrod

AbstractApoferritin (apoF) is commonly used as a test specimen in single-particle electron cryo-microscopy (cryo-EM), since it consistently produces density maps that go to 0.3 nm resolution or higher. When we imaged apoF with a laser phase plate (LPP), however, we observed more severe particle-to-particle variation in the images than we had previously thought to exist.