Jerome Staal

A rare case of asymptomatic dominantly inherited #Alzheimer's reveals confined tau pathology and unique proteomic features, highlighting potential resilience mechanisms decades beyond expected onset. @WashUMedADRC @jorgellibre https://t.co/VdsHbfN9px #Resilience

RT @SuzanneESchind1: There is a misconception that only amyloid-targeting treatments have been studied in Alzheimer's disease. The reality…

RT @LukensJohnR: A man was destined for early Alzheimer’s ― these genes might explain his escape https://t.co/ImDf9j8yMP

🔬 New study from @tommykakari and colleagues identifies a core amino acid sequence that defines pre-tangle tau aggregates, revealing phospho-tau serine-262 & serine-356 as novel early-stage biomarkers. #Tau #Alzheimers #Biomarkers #EarlyDetection @PittPsychiatry https://t.co/BzIrawfPnv

🌟Exciting new study show that that somatic CAG repeat expansion measured longitudinally in blood is a key driver of the effect of CAG repeat length on markers of very early #neurodegeneration in #HuntingtonsDisease. @UCLHD @UCLIoN https://t.co/EZTQqqGw18

RT @Qi_Tsinghua: Excited to share our study @Nature, https://t.co/32RzJi5IbO functionally defining a new memory CD8 subset, a novel CD8 T c…

🥤Another interesting read for today is a new study looking at the burden of type 2 #diabetes and #cardiovascular disease attributed to sugar-sweetened beverages in 184 countries. #sugar #sweeteners https://t.co/zQ1pxsyaHC

🌟Check out this interesting paper on the development of a #BaseEditing approach for the treatment of #PrionDisease. Great (and important) work @davidrliu @cureffi @prionalliance @DevermanLab #Prion #GeneTherapy https://t.co/SdcnUpX6VV

Great work from @JoeCoresh, @LizSelvin, and team for providing contemporary lifetime risk estimates for #dementia in the US, including one of the first lifetime risk estimates for Non-Hispanic Black adults. @JHUWelchCenter @nyulangone https://t.co/srBNUy4qXc

#LiverTransplantation is the only available treatment for end-stage liver disease. Here researchers from @EdinUni_IRR report the safety and efficacy of autologous monocyte-derived #macrophage therapy for #LiverCirrhosis in a phase 2 clinical trial https://t.co/KCiIHbowlG

RT @JAMA_current: 18.5% of patients who left the emergency department without being seen returned within 7 days, often due to difficulties…

RT @saraheeberry: Our new research out today in @NatureMicrobiol led by @nsegata expanding our knowledge on diet-microbiome-health connecti…

Fascinating new study reports promising findings from a phase 1/2 trial of a new device/pump that delivers anaerobic #dopamine directly to the brain of individuals with #ParkinsonsDisease, reducing L-dopa-related complications. #PD @univ_lille @inbrainpharma @CaroMoreux

By simulating realistic patient-doctor interactions, a framework can be applied to large language models to identify potential biases and shortcomings in patient communication, offering valuable insights before clinical deployment. #LLMs #DigitalMedicine https://t.co/jsdVSpfwRx

RT @EricTopol: 11 clinical trials to watch in 2025 @NatureMedicine https://t.co/3Ndvv5lI34 https://t.co/oPDBHoesDn

Check out this new study in @NatureMedicine showing that #DeepBrainStimulation of the #hypothalamus promotes motor recovery in preclinical models and humans following #SpinalCordInjury. Great work from @gcourtine & Jocelyne Bloch @_NeuroRestore #SCI #TBI https://t.co/UryIP7kP1S

Check out this new atlas of the first trimester human #placenta! It's packed with insights on early #PlacentalDevelopment and #pregnancy. Great work from @JianShuLab and team at @harvardmed @insitubiology! 🌟 More info here: https://t.co/U3fTfs8cbQ