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1 month ago | 
hmpgloballearningnetwork.com | Jessica Garlewicz
A recent study published in RMD Open, evaluating patients with psoriasis (PsO) and subclinical psoriatic arthritis (PsA), highlights the elevated risk of developing PsA in this population. The findings emphasize the importance of monitoring musculoskeletal symptoms in patients with PsO to facilitate early detection and intervention. The study followed 384 patients with PsO for an average of 33 months, with 311 (80.9%) classified as having subclinical PsA.
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1 month ago | 
hmpgloballearningnetwork.com | Jessica Garlewicz
News A randomized trial published in Gastroenterology comparing ultrasonography (US) and noncontrast magnetic resonance imaging (MRI) for liver cancer surveillance in cirrhotic patients has found MRI offers significant advantages, including earlier tumor detection and fewer false-positive referrals. These findings could influence surveillance protocols for at-risk patients.
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1 month ago | 
hmpgloballearningnetwork.com | Jessica Garlewicz
A decade-long observational study published in Rheumatology confirms that disease activity-guided dose optimization of tumor necrosis factor (TNF) inhibitors in rheumatoid arthritis (RA) is both safe and effective, allowing for significant dose reductions without compromising disease control. The study followed 170 patients, with 127 completing the 10-year assessment. Disease activity remained consistently low, with a mean DAS28-CRP of 2.13.
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1 month ago | 
hmpgloballearningnetwork.com | Jessica Garlewicz
A new modeling study published in JAMA Network Open projects a significant increase in the prevalence and clinical impact of metabolic dysfunction–associated steatotic liver disease (MASLD) among U.S. adults over the next 3 decades. Published results indicate that MASLD will increasingly drive rates of hepatocellular carcinoma (HCC), liver transplant (LT), and liver-related mortality, underscoring the urgency of advancing prevention and treatment strategies.
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1 month ago | 
hmpgloballearningnetwork.com | Jessica Garlewicz
News A new study published in utilizing advanced MRI-based methods highlights the significant burden of steatotic liver disease (SLD) in overweight and obese adults in the U.S., with notable rates of advanced fibrosis and cirrhosis. The cross-sectional analysis included 539 community-dwelling adults aged 40–75 years with a mean BMI of 32.6 kg/m².
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1 month ago | 
hmpgloballearningnetwork.com | Jessica Garlewicz
A recent study published in The American Journal of Gastroenterology emphasizes the need for a risk-based approach to evaluating and managing metabolic dysfunction-associated steatotic liver disease (MASLD), including its progressive form, metabolic dysfunction-associated steatohepatitis (MASH). This approach aims to address the underlying metaboinflammatory state driving liver injury and to prioritize fibrosis regression as a key treatment objective.
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1 month ago | 
hmpgloballearningnetwork.com | Jessica Garlewicz
News A study leveraging data from Swedish family cancer datasets has shown a significant association between the frequency of polyp diagnoses in family members and an increased risk of colorectal cancer (CRC), particularly early-onset CRC. Published in Gastroenterology, the findings, based on more than 5 decades of follow-up involving 11.7 million individuals, emphasize the need for personalized CRC screening strategies tailored to family history.
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1 month ago | 
hmpgloballearningnetwork.com | Jessica Garlewicz
A new study evaluating the relationship between perineural invasion (PNI) score and adverse events (AE) in cutaneous squamous cell carcinoma (cSCC), presented at the 2025 AAD Annual Conference, found no statistically significant association. These findings do not support the predictive value of the composite PNI score for metastasis, recurrence, or disease-related death in patients with cSCC. The study sought to validate the Totonchy et al.
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1 month ago | 
hmpgloballearningnetwork.com | Jessica Garlewicz
A multidisciplinary expert group has developed new evidence-based recommendations to complement existing guidelines for psoriatic arthritis (PsA) management, addressing key gaps in routine clinical practice. The consensus statements, published in Rheumatology, covering diagnosis, assessment, comorbidities, and management, emphasize early identification, holistic disease evaluation, and multidisciplinary care.
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1 month ago | 
hmpgloballearningnetwork.com | Jessica Garlewicz
In this interview, Jane Margaret Grant-Kels, MD, FAAD, discusses the unique screening challenges, the importance of early detection, and strategies for reducing disparities in melanoma outcomes. Learn practical approaches for improving diagnosis, leveraging dermoscopy, and enhancing patient education in high-risk groups. Dr Grant-Kels is a professor of dermatology, pathology, and pediatrics at UConn Health in Farmington, CT.
