Jessica Kelley

Dec 19, 2024 | cell.com | Jessica Kelley |Emilia Dimitrova |Hieu Nguyen |Hiếu Nguyễn |Aleksander T Szczurek |Amy Hughes | +4 more

Sep 11, 2024 | nature.com | Aleksander T Szczurek |Emilia Dimitrova |Jessica Kelley

AbstractThe Polycomb system has fundamental roles in regulating gene expression during mammalian development. However, how it controls transcription to enable gene repression has remained enigmatic. Here, using rapid degron-based depletion coupled with live-cell transcription imaging and single-particle tracking, we show how the Polycomb system controls transcription in single cells.