Jessica Mak

Jan 13, 2025 | biorxiv.org | Danella M. Hafeman |Jamie Feldman |Jessica Mak |John Merranko

AbstractBipolar disorder (BD) is characterized by temporal instability of mood and energy, but the neural correlates of this instability are poorly understood. In previous cross-sectional studies, mood state in BD has been associated with differential functional connectivity (FC) amongst several subcortical regions and ventromedial prefrontal cortex. Here, we assess whether BD is associated with longitudinal instability within this mood-related network of interest (NOI).

Feb 13, 2024 | biologicalpsychiatryjournal.com | Danella M. Hafeman |Jamie Feldman |John Merranko |Jessica Mak

Bipolar disorder (BD) is characterized by temporal instability of mood and energy, but the neural correlates of this instability are poorly understood. In previous cross-sectional studies, mania has been correlated with increased functional connectivity (FC) of regions key to reward processing. Here, we assess whether BD is associated with longitudinal instability within a reward-related network of interest (NOI).