Jiabao Du

Aug 4, 2024 | onlinelibrary.wiley.com | Hongwei Cheng |Northwest Xi'an |Xiangbo Li |Jiabao Du

1 INTRODUCTION The skin constitutes approximately 15% of the total body weight in humans and serves as a vital interface with the external environment, functioning as a primary defense system.1 Its pivotal role encompasses not only the prevention of entry for harmful agents such as ultraviolet radiation, microbial pathogens, and antigens but also the regulation of body homeostasis. The skin comprises the epidermis, the dermis, and subcutaneous tissues in the structure.