Jiahn Choi

Nov 25, 2024 | onclive.com | Leonard H Augenlicht |Ziv Cohen |Sarah Quiñones Wolfson |Jiahn Choi

Over the past 15 years, colorectal cancer (CRC) diagnoses have risen among men and women aged 40 years and older, and even among younger individuals.1 Currently, people born after 1990 are twice as likely to be diagnosed with CRC— and 4 times as likely to develop rectal cancer—as those born in 1950, according to the American Cancer Society (ACS). The ACS estimates about 107,000 new cases of colon cancer and 46,220 new cases of rectal cancer in the US in 2024.

Feb 29, 2024 | nature.com | Jiahn Choi

AbstractThe intestinal epithelium is the first line of defense and acts as an interface between the vast microbial world within the gastrointestinal tract and the body’s internal milieu. The intestinal epithelium not only facilitates nutrient absorption but also plays a key role in defending against pathogens and regulating the immune system.