Jiane Liu

Dec 3, 2024 | onlinelibrary.wiley.com | Yiming Zhang |Jing Li |Jiane Liu |Yan Gao

1 Introduction Osteoarthritis (OA) has become one of the most common diseases, affecting more than 500 million people worldwide [1]. This chronic degenerative disease compromises the entire synovial joint with key features of articular cartilage destruction, synovial inflammation, subchondral bone remodelling, osteophyte formation, joint space narrowing and tendons and ligaments instability [2, 3].