Jiangwen Zhang

Nov 12, 2024 | onlinelibrary.wiley.com | Xinyi Bi |Teresa Ooi |Suen Chan |Jiangwen Zhang

Conflicts of Interest The authors declare no conflicts of interest. References , , , et al. 2022. “Muscle-Generated BDNF (Brain Derived Neurotrophic Factor) Maintains Mitochondrial Quality Control in Female Mice.” Autophagy 18: 1367–1384. https://doi.org/10.1080/15548627.2021.1985257. , , , et al. 2021. “Regulation of Estradiol Synthesis by Aromatase Interacting Partner in Breast (AIPB).” Molecular and Cellular Biology 41, no. 11: e0035721. https://doi.org/10.1128/MCB.00357-21.

Jun 3, 2024 | biorxiv.org | Jing Ma |Kun Wang |Jiangwen Zhang |Susan Yung

AbstractPeritoneal metastasis exacerbates the prognosis of ovarian cancer patients. Adhesion of cancer cells to mesothelium is a rate-limiting prerequisite for this process. How metastatic cells sense and respond to the dynamic biomechanical microenvironment at the mesothelial niche to initiate metastatic lesions remains unclear. Here, the study demonstrates that highly metastatic (HM), but not non–metastatic (NM) ovarian cancer cells, selectively activate the peritoneal mesothelium.