Jianye Han

Aug 23, 2024 | aging-us.com | Weiwei Yuan |Jianye Han |CHEN CHEN |Yue Qiu

Background: Ubiquitination is a targeted protein modification process mediated by intracellular molecules. UBR1 encodes a protein that binds to unstable N-terminal residues of substrate proteins and contributes to the formation of substrate-linked polyubiquitin chains. However, the function and cellular pathways of UBR1 in tumors have received inadequate attention.

Aug 23, 2024 | aging-us.com | Weiwei Yuan |Jianye Han |CHEN CHEN |Yue Qiu

Research Paper Volume 16, Issue 16 pp 12029—12049 1 Department of Thyroid Surgery, Baoshan Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201999, China 2 Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Anhui Public Health Clinical Center, Hefei 230012, China 3 Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China * Equal contribution...