Jiayan Liao

Oct 9, 2023 | nature.com | xun zhang |Jiayan Liao |Jiajia Zhou |Chao Liu

AbstractSkeletal disorders are commonly diagnosed by X-ray imaging, but the radiation limits its use. Optical imaging through the near-infrared-II window (NIR-II, 1000–1700 nm) can penetrate deep tissues without radiation risk, but the targeting of contrast agent is non-specific. Here, we report that lanthanide-doped nanocrystals can passively target the bone marrow, which can be effective for over two months.