Jiayi Shen

Sep 10, 2024 | digitalcommons.library.tmc.edu | Anqi Wang |Jiayi Shen |Alex Rodriguez |Alex Rodríguez |Edward Saunders

The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry genome-wide association study of 156,319 prostate cancer cases and 788,443 controls of European, African, Asian and Hispanic men, reflecting a 57% increase in the number of non-European cases over previous prostate cancer genome-wide association studies.

Apr 12, 2024 | onlinelibrary.wiley.com | Jiayi Shen |Lai Jiang |Kan Wang |Anqi Wang

1 INTRODUCTION The development of high-throughput genotyping and genotype imputation has boosted the application of genome-wide association studies (GWAS) which is now a standard approach to identify susceptibility loci or genomic regions for many complex diseases and traits (Buniello et al., 2019; Schaid et al., 2018).

Dec 22, 2023 | univ-rennes.hal.science | Anqi Wang |Jiayi Shen |Alex Rodriguez |Alex Rodríguez |Edward Saunders

Article Dans Une Revue Nature Genetics Année : 2023 Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants hal-04361167 , version 1 (22-12-2023) Anqi Wang, Jiayi Shen, Alex Rodriguez, Edward Saunders, Fei Chen, et al.. Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants. Nature Genetics, 2023, 55 (12), pp.2065-2074. ⟨10.1038/s41588-023-01534-4⟩.