Jiayin Gao

Jul 19, 2024 | biorxiv.org | Jiayin Gao |Jiawei Wang |Shiyu Liu |Jinzhu Song

AbstractThe first cell-fate decision is the process by which cells of an embryo take on distinct lineage identities for the first time, thus representing the beginning of developmental patterning. Here, we demonstrate that the molecular chaperone heat shock protein A2 (HSPA2), a member of the 70 kDa heat shock protein (HSP70) family, is asymmetrically expressed in the late 2-cell stage of mouse embryos.