Jim Catalfamo

Dec 5, 2024 | onlinelibrary.wiley.com | Marjory B. Brooks |James Brooks |Jim Catalfamo |Yao Zhu

We appreciate Dr. Wun's interest in our article and the opportunity to clarify the thrombopoietin assay's configuration. Dr. Wun raises a concern regarding the addition of cryopoor plasma to the canine plasma samples. There was no addition of cryopoor plasma to any of the canine plasma samples, including plasma from healthy dogs, ITP dogs, or spike-and-recovery plasmas. All canine plasma samples were diluted in assay buffer alone.

Aug 14, 2024 | onlinelibrary.wiley.com | Marjory B. Brooks |James Brooks |Yao Zhu |Jim Catalfamo

BSA bovine serum albumin HRP horseradish peroxidase LOD limit of detection LOQ limit of quantitation MS mass spectrometry PBST phosphate-buffered saline with 0.5% Tween pITP primary immune thrombocytopenia rcTPO recombinant canine thrombopoietin TBS tris-buffered saline TPO thrombopoietin 1 INTRODUCTION Primary immune thrombocytopenia (pITP) is an immune-mediated bleeding disorder characterized by isolated thrombocytopenia without an initiating or underlying cause.1 In dogs, pITP causes...