Jinghan Diao

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Identification and characterization of the de novo methyltransferases for eukaryotic N6-methyladenine (6mA)

Mar 25, 2024 | biorxiv.org | Ting Cheng |Jiachen Zhang |Haicheng Li |Jinghan Diao

AbstractDNA N6-adenine methylation (6mA) is rediscovered as an important epigenetic mark in eukaryotes. We previously identified the MT-A70 family member AMT1 as the maintenance methyltransferase (MTase), but the identity of the de novo MTase(s) for 6mA establishment remains unidentified.

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