Jinhua Wu

Dec 22, 2024 | mdpi.com | Jinhua Wu

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Oct 1, 2024 | biorxiv.org | Jinhua Wu

AbstractIntegrins consist of 24 species, each with unique tissue-expression profiles and distinct biological functions. The β subunit of integrin interacts with the FERM-folded head domain of talin through an N-P-x-Y/F motif, triggering integrin activation. Although this motif is conserved across most integrin-β subunits, the precise molecular mechanisms governing talin's selective recognition of different integrin species remains unclear.

May 28, 2024 | biorxiv.org | Jinhua Wu

AbstractIntegrins consists of 24 species with diverse tissue-expression profiles and distinct biological functions. The β subunit of integrin interacts with the FERM-folded head domain of talin through an N-P-x-Y/F motif, triggering integrin activation. Although this motif is conserved across most integrin-β subunits, the detailed molecular mechanisms governing the specific recognition of different integrin species by talin remains unclear.

May 9, 2024 | mdpi.com | Feng Jiao |Dongdong Zhang |Yang Chen |Jinhua Wu

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May 2, 2024 | mdpi.com | Jinhua Wu |Can Wang |Xiong He |Chunshan Zhou

1. IntroductionIn the context of societal advancement and progress, the ever-growing human aspiration for wealth accumulation and the pressing need for development exert considerable pressure on finite land resources. This escalation intensifies tensions within the human–land interaction, exacerbating conflicts between humanity and the land. Since the Industrial Revolution, these contradictions and conflicts have rapidly transcended local boundaries to a global scale.