Jinye Liang

1 week ago | biorxiv.org | Lindsey F. Snyder |Emily O'Brien |Jia Zhao |Jinye Liang

AbstractCombinatorial control by transcription factors (TFs) is central to eukaryotic gene regulation, yet its mechanism, evolution, and regulatory impact are not well understood. Here we use natural variation in the yeast phosphate starvation (PHO) response to examine the genetic basis and species variation in TF interdependence.