Jinyong Choi

Nov 28, 2024 | cell.com | Caterina E. Faliti |Jinyong Choi |Simon Belanger |Christopher M. Tipton |Sakeenah L. Hicks |Maria Cardenas | +17 more

KeywordsantibodiesvaccineCD4 T cellsT follicular helper cellsTfh cellsplasma cellsIL-2 cytokinemTORmetabolismGet full text accessLog in, subscribe or purchase for full access. References1. Radbruch, A. ∙ Muehlinghaus, G. ∙ Luger, E.O. ... Competence and competition: the challenge of becoming a long-lived plasma cellNat. Rev. Immunol. 2006; 6:741-7502. Slifka, M.K. ∙ Antia, R. ∙ Whitmire, J.K. ... Humoral immunity due to long-lived plasma cellsImmunity. 1998; 8:363-3723.

Jun 2, 2024 | nature.com | Jinyong Choi

AbstractInside germinal centers (GCs), antigen-specific B cells rely on precise interactions with immune cells and strategic localization between the dark and light zones to clonally expand, undergo affinity maturation, and differentiate into long-lived plasma cells or memory B cells.